Major Changes
This release adds options to filter loss-of-heterozygosity and gain-of-reference allele calls from SomaticSniper output. Loss-of-heterozygosity calls are defined as calls where the tumor genotype is fully a subset of the normal genotype. Gain-of-heterozygosity calls are defined as those where the reference allele is not present in the normal genotype call, but is present in the tumor. For example the following calls would both be suppressed,
Ref | Tumor | Normal |
---|---|---|
A | GG | AG |
A | AG | GG |
Minor Changes
- build-common is now utilized as a git subtree. Downloads from github will now be functional and recursive clones are no longer necessary.
You can download this release on Github.